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How to save the vision of diabetic patients

Nowadays, diabetes has received the attention and attention of the society. As the disease progresses, the threat of complications will increase.

Changes in blood glucose levels over a long period of time can cause damage to the retinal small blood vessels in the fundus, which can cause severe vision loss.

The data show that one-third of diabetic patients develop diabetic retinopathy, and diabetic macular edema (DME) is one of the most common and serious complications of diabetic retinopathy.




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According to Professor Xu Xun, deputy director of the Ophthalmology Branch of the Chinese Medical Association and director of the fundus group, the hyperglycemia status of diabetic patients affects the blood vessels and nerves of the whole body, including the blood vessels and nerves in the fundus. About one-third of people with diabetes have diabetic retinopathy (DR), and about one-third of them have DME.

As of 2017, according to epidemiological statistics, it is estimated that there are about 710,000 DME patients with clinical significance in the diagnosis of diabetes in China. These fundus lesions can cause irreversible effects on the patient's vision.

Therefore, diabetic patients are at high risk of visual impairment. The visual management of patients with diabetic macular edema should be paid more attention.

What is the macula? Why do edema of the macula in diabetic patients?

The macula is the most sensitive area of vision in the center of each of our eyes. The occurrence of DME is closely related to the course of diabetes and the severity of diabetic retinopathy.

In other words, the longer a person has diabetes, the more likely it is to develop DME, and the more severe the diabetic retinopathy, the more likely it is to develop DME.

DME is also caused by damage to the vasculature of the retina due to unstable blood glucose levels, which increases the permeability of the blood retina, which increases the permeability of the blood retina, and the effusion (permeate) enters the macula. Thereby causing diabetic macular edema. It is conceivable that in such a sharp area of the macula, diabetic macular edema will seriously affect vision.




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Why does diabetic macular edema need early treatment?

Diabetic macular edema (DME) can cause severe vision loss, mainly in the center of the field of vision, there will be dark spots, that is, patchy blurred vision, it is difficult to see details clearly, including close and long distance.

The contrast sensitivity will decrease, the color seen will be dim and faded, the color of the object will change, and the darkness will be felt; the shape of the object will change, sometimes it will become larger than the actual shape, sometimes It also becomes smaller, and the line appears wavy or broken in some parts of the field of view. These symptoms of DME patients will seriously affect the quality of life of patients, affect the normal working conditions, and bring a heavy burden to the family and society as a whole.

Vision loss caused by diabetic macular edema (DME)

Diabetic macular edema (DME) is treatable

Before 2012, doctors could only use lasers to treat DME. Although laser treatment can prevent DME from further progress, it can not restore or improve the visual acuity of DME patients, and may lead to retinal damage, etc., further affecting visual adverse events, and clinically urgently needed new treatments.

In recent years, with the emergence of anti-VEGF drugs such as aboxicept, local anti-VEGF injection has become the first-line treatment of DME. The investigation found that patients with diabetic macular edema, if they do not have effective intervention, lose their ability to work first, and then lose their ability to take care of themselves, and bring a huge burden of care.

New treatments for anti-VEGF to bring vision benefits to patients with DME Treatment of fundus diseases was once the most difficult area of ophthalmology.




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In recent years, with the advancement of technology and drugs, some innovative methods have been applied in China. Professor Dai Hong, director of the ophthalmology department of Beijing Hospital, said: DME is caused by microvascular exudation and neovascularization in the macular area. The main goal of abecept is to fight and block the vascular endothelial growth factor protein called VEGF, thereby reducing the number of newborns.

Blood vessels grow and resolve DME edema, making the patient's condition no longer develop. Compared with laser treatment, its biggest advantage is that it can reverse the disease and restore the visual function that some patients have lost. Even severe DME can improve vision and improve the quality of life.